Deji Adeyanju, an Abuja-based activist, said Osinbajo and Tinubu should step down in favour of the South-East.
He was reacting to calls that the APC and the Peoples Democratic Party, PDP, should zone their presidential tickets to the South.
The rights activist said such calls were a waste of time.
In a Facebook post, Adeyanju stressed that such calls would only unite the North.
According to Adeyanju: “The protests demanding for Southern presidency at both APC and PDP secretariats are a waste of time. It will only unite the North.
“The best way to ensure South gets presidency is for Tinubu, Osinbajo and others to step down their ambition for South-East in the interest of equity.”